Neuroinflammation mechanisms of neuromodulation therapies for anxiety and depression

HIGHLIGHTS

  • who: Bingqi Guo from the (UNIVERSITY) have published the research work: Neuroinflammation mechanisms of neuromodulation therapies for anxiety and depression, in the Journal: (JOURNAL) of 17/09/2022
  • what: In a meta-analysis encompassing multiple animal models of stress, all studies showed increased expression of the microglial cell surface marker ionized calcium-binding adapter molecule 1 (Iba1) in the hippocampus, and 75% of the studies showed increased Iba1 in the prefrontal cortex .
  • how: The results showed that TSPO VT was significantly higher in the prefrontal cortex ACC and insula suggesting microglial activation with . . .

     

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