Neuromuscular junction impairment in amyotrophic lateral sclerosis: reassessing the role of acetylcholinesterase

HIGHLIGHTS

  • who: Maria-Letizia Campanari and Edor Kabashi from the Universidad Miguel Hernu00e1ndez-CSIC, Sant Joan d`Alacant, Spain, Centro de Investigaciu00f3n Biomu00e9dica en Red sobre have published the paper: Neuromuscular Junction Impairment in Amyotrophic Lateral Sclerosis: Reassessing the Role of Acetylcholinesterase, in the Journal: (JOURNAL) of 15/09/2016

SUMMARY

    The vertebrate neuromuscular junction (NMJ) is a "tripartite" synapse, composed by the presynaptic motorneuron (MN), the postsynaptic muscle, and the synapse-associated glial cells (terminal Schwann cells, TSC; Castonguay et_al, 2001; Jessen and Mirsky, 2005). The main form at NMJs is asymmetrical, consisting . . .

     

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