Neuromuscular junction pathology is correlated with differential motor unit vulnerability in spinal and bulbar muscular atrophy

HIGHLIGHTS

• who: Elana Molotsky from the Animal care and experimental procedures were conducted in accordance with the Thomas Jefferson University Institutional Animal Care and Use Committee (IACUC)Transgenic Model: The transgenic model, previously described in Chevalier-Larsen et_al, [5], uses the prion protein promoter to express an expanded human AR containing , CAG repeats (+ , CAA codon, encoding a total of , glutamine residues within the human AR protein) primarily in the central nervous system. Knock-in Model: The knock-in model, previously described in Yu et_al, [74, ], replaces part of the exon , of the mouse androgen receptor gene with a . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.