Neuron-oligodendrocyte potassium shuttling at nodes of ranvier protects against inflammatory demyelination

HIGHLIGHTS

• who: Hannah Kapell and colleagues from the GermanyDepartment of Neurology, of Du00fcsseldorf, Germany have published the Article: Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination, in the Journal: (JOURNAL)
• what: OL-KIR4.1 downregulation at MS lesion rims and worsened EAE in animals with ablated OL-Kcnj10 function To study KIR4.1 channel IR in MS ON samples, the authors focused on lesion rim areas and observed a reduction of OL-KIR4.1 IR at NAWM and PPWM areas (average MS 9 disease duration approximately 25 years) relative to controls . The . . .
  

   

  

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