Neuronal ablation of coa synthase causes motor deficits, iron dyshomeostasis, and mitochondrial dysfunctions in a copan mouse model

HIGHLIGHTS

• who: Ivano Di Meo et al. from the Institut des Sciences Analytiques, Univ Lyon, CNRS, Université Claude Bernard Lyon, UMR, rue de Raffaele University, Milan, Italy have published the article: Neuronal Ablation of CoA Synthase Causes Motor Deficits, Iron Dyshomeostasis, and Mitochondrial Dysfunctions in a CoPAN Mouse Model, in the Journal: (JOURNAL)
• how: Since COASY is the only gene so far known to encode for CoA synthase in mammals the authors hypothesized that a mouse model defective for this enzyme could display a pathological phenotype. To verify if neuronal Coasy deficiency leads to impairment of . . .
  

   

  

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