HIGHLIGHTS
- who: Anthony N. Moore from the (UNIVERSITY) have published the research work: Neuronal Activity Increases the Phosphorylation of the Transcription Factor cAMP Response Element-binding Protein (CREB) in Rat Hippocampus and Cortex*, in the Journal: (JOURNAL) of July/24,/1995
- what: Using an antibody that detects Ser133-phosphorylated CREB protein, the authors show that CREB phosphorylation is maximal between 3 and 8 min after the onset of seizure activity and declines slowly both in the hippocampus and the cortex.
- future: Future experiments will help determine if calcium-sensitive adenylyl cyclases are indeed activated . . .
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