Neuronal haemoglobin induces loss of dopaminergic neurons in mouse substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein

HIGHLIGHTS

• who: Chiara Santulli from the Department University of have published the research work: Neuronal haemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous u03b1-synuclein, in the Journal: (JOURNAL) of 10/05/2022
• what: The authors show that a prolonged ectopic expression of Hb in rodent SNpc induces the loss of DA neurons along with motor and cognitive impairments. Sample sizes used in this study were based on previous behavioural studies that showed the minimum number of mice needed to show a significant difference. In the present study . . .
  

   

  

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