HIGHLIGHTS
- who: Viswanathan from the Department of Clinical Neurosciences and Cambridge University Hospitals NHS Trust, University of Cambridge, UK have published the research work: Neurophysiological consequences of synapse loss in progressive supranuclear palsy, in the Journal: (JOURNAL)
- what: Using parametric empirical Bayesian inversion of a conductance-based canonical microcircuit model of magnetoencephalography data the authors show that the inclusion of regional synaptic density-as a subject-specific prior on laminar specific neuronal populations-markedly increases model evidence. The method the authors demonstrate is not restricted to progressive supranuclear palsy or the effects of synaptic loss: such . . .
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