HIGHLIGHTS
SUMMARY
Interestingly, recent studies have shown that integrins and neuropilin-1 may also act as important receptors for CgA, vasostatin-1, CgA1-373, and other fragments, in endothelial cell biology, cardiovascular function, angiogenesis, wound healing, and tumor growth. No interaction of full-length CgA and CgA1-372 with neuropilin-1 occurs, indicating that the PGPQLR373 binding_site is cryptic in the fulllength precursor and that the C-terminal arginine residue (R373, which is absent in CgA372 ) is necessary for the binding. This interaction might occur on αvβ3-positive endothelial cell after the interaction with other . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.