Neuropilin-1 modulates the 3d invasive properties of glioblastoma stem-like cells

HIGHLIGHTS

  • who: September et al. from the (CRBM), France University of Rome Tor Vergata, Italy have published the article: Neuropilin-1 modulates the 3D invasive properties of glioblastoma stem-like cells, in the Journal: (JOURNAL)
  • how: The authors evaluated whether these experimental settings can be challenged with genetic and pharmacological manipulation of patient cells.
  • future: Future works are required to determine the underlying mechanisms of NRP1-driven ITGB3 downregulation.

SUMMARY

    A quantitative and qualitative variety of extracellular proteins, including hyaluronan, vitronectin, collagens, and tenascin contribute to the adhesive and infiltrative . . .

     

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