Neuroprotective effect of mealworm protein hydrolysate-derived bioactive peptides in human microglial cells

HIGHLIGHTS

• What: In this study the effect of a digested hydrolysate on microglia cells (which previously demonstrated high antiinflammatory activity in intestinal CACO-2 cells) was analysed specifically on their levels of gene expression of various cytokines such as IL-6 IL-10 or IL-1β among others. The aim of this study was therefore to evaluate the anti-inflammatory activity in cells of the central nervous system that function as elements of the immune system (microglia) by analysing the regulation in the gene_expression of pro and anti-inflammatory cytokines, which can be exerted by selected peptides, and . . .
  

   

  

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