Neuroprotective effects and metabolomics study of protopanaxatriol (ppt) on cerebral ischemia/reperfusion injury in vitro and in vivo

HIGHLIGHTS

  • who: Fulin Wu and colleagues from the School of Pharmaceutical Sciences, Jilin University, Changchun, China have published the paper: Neuroprotective Effects and Metabolomics Study of Protopanaxatriol (PPT) on Cerebral Ischemia/Reperfusion Injury In Vitro and In Vivo, in the Journal: (JOURNAL)
  • what: The authors established an oxygen-glucose deprivation (OGD)-PC12 cell model and middle artery occlusion/reperfusion (MCAO/R) model to evaluate the neuroprotective effects of in vitro and in vivo. The research shows that PPT can improve these inflammatory and oxidative factors, indicating that PPT can resist CIR injury by anti-oxidative stress . . .

     

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