Neuroprotective effects of 17β-estradiol rely on estrogen receptor membrane initiated signals

HIGHLIGHTS

  • who: Maria Marino from the Department of Biology, University Roma Tre, Roma, Italy have published the article: Neuroprotective effects of 17β-estradiol rely on estrogen receptor membrane initiated signals, in the Journal: (JOURNAL)
  • what: In mammals, E2 exerts a profound influence on multiple brain circuits involved in reproductive and non-reproductive physiology and behavior.

SUMMARY

    E2 elicits either organizational effects during embryonic and neonatal development or the activational control of gene_expression during the later stages of life cycle by regulating synaptic transmission, neuronal survival, neuronal, and glial differentiation (Garcia-Segura et_al . . .

     

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