Neuroprotective effects of a novel demeclocycline derivative lacking antibiotic activity: from a hit to a promising lead compound

HIGHLIGHTS

• who: Rodrigo Tomas-Grau and colleagues from the Instituto de Investigaciu00f3n en Medicina Molecular y Celular Aplicada (IMMCA) (CONICET-UNT-SIPROSA), Pasaje Dorrego, San Miguel de Tucumu00e1n, Argentina have published the article: Neuroprotective Effects of a Novel Demeclocycline Derivative Lacking Antibiotic Activity: From a Hit to a Promising Lead Compound, in the Journal: Cells 2022, 2759 of 28/07/2022
• what: The authors aimed to advance the hit DMC compound towards a lead molecule with improved neuroprotective properties and minimal antibiotic activity, thus taking advantage of the neuroprotective potential of DMC while avoiding the antibiotic . . .
  

   

  

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