Neuroprotective properties of bis-sulfonamide derivatives against 6-ohda-induced parkinson`s model via sirtuin 1 activity and in silico pharmacokinetic properties

HIGHLIGHTS

  • who: Ratchanok Pingaew and Kamonrat Phopin from the Universidad de Sevilla, Spain have published the article: Neuroprotective Properties of Bis-Sulfonamide Derivatives Against 6-OHDA-Induced Parkinson`s Model via Sirtuin 1 Activity and in silico Pharmacokinetic Properties, in the Journal: (JOURNAL)
  • what: In this study, a series of 17 bis-sulfonamide derivatives (1- 17, Figure 1) previously reported by the group (Leechaisit et_al, 2019) were investigated for their neuroprotective effects and underlying possible mechanisms against the 6-OHDA-induced (Albers and Beal, 2000; Baker and Petersen, 2018). In this study, a set of 17 . . .

     

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