Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte-neuron communication

HIGHLIGHTS

• who: Mediates Oligodendrocyte-Neuron Communication and colleagues from the Department of Molecular Cell Biology, University of Mainz, Mainz, Germany, Focus Program Translational Neuroscience, University of Mainz, Mainz, Germany, Max have published the paper: Neurotransmitter-Triggered Transfer of Exosomes Mediates Oligodendrocyte-Neuron Communication, in the Journal: (JOURNAL) of April/19,/2013
• what: The authors show that activity-dependent release of the neurotransmitter glutamate triggers oligodendroglial exosome secretion mediated by Ca2+ entry through oligodendroglial NMDA and AMPA receptors. This study explores the possibility of horizontal transfer of molecules from oligodendrocytes to neurons by vesicles secreted from MVBs . . .
  

   

  

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