Neutralisation hierarchy of sars-cov-2 variants of concern using standardised, quantitative neutralisation assays reveals a correlation with disease severity; towards deciphering protective antibody thresholds

HIGHLIGHTS

  • who: Diego Cantoni from the University of Milan, Italy have published the research: Neutralisation Hierarchy of SARS-CoV-2 Variants of Concern Using Standardised, Quantitative Neutralisation Assays Reveals a Correlation With Disease Severity; Towards Deciphering Protective Antibody Thresholds, in the Journal: (JOURNAL)
  • how: For this the authors used a linear mixed model similar to the one described above but using WHO clinical COVID-19 severity scores on the combined group of HCWs and patients. calibrant to have its own IC50 value and its own gradient and one where a single gradient was shared between calibrants . . .

     

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