Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating dna

HIGHLIGHTS

  • who: Ekaterina Pisareva from the , Montpellier, France have published the Article: Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA, in the Journal: (JOURNAL)
  • what: In this study (Fig 1), the authors used the synergistic analytical information provided by qPCR, sWGS, and capillary electrophoresis to unequivocally observe the following: the kinetics of genomic DNA degradation by serum nucleases in_vitro; the production of extracellular DNA (or cfDNA) by ex vivo activated neutrophils; the in_vitro NET degradation by serum nucleases. As part of the study , the authors also investigated the kinetics of in_vitro . . .

     

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