Neutrophil-specific knockdown of β2 integrins impairs antifungal effector functions and aggravates the course of invasive pulm

HIGHLIGHTS

• who: Maximilian Haist from the University of Tennessee College of Medicine, United States have published the Article: Neutrophil-Specific Knockdown of u03b22 Integrins Impairs Antifungal Effector Functions and Aggravates the Course of Invasive Pulm, in the Journal: (JOURNAL)
• what: The authors show that mice with a Ly6G-specific knockdown of CD18 (CD18Ly6G conditional knockout, in the following termed CD18Ly6G cKO) display an impaired survival during IPA as compared to control-mice (CD18fl/fl). For the experiments, mice of both sexes were used, although most experiments were done with female mice. The percentages of monocytic and . . .
  

   

  

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