HIGHLIGHTS
- who: David A. Clément et al. from the Institut Pasteur, Unité de Chimie et Biocatalyse, CNRS, Paris, France have published the research: New Chemical Probe Targeting Bacterial NAD Kinase, in the Journal: (JOURNAL)
- what: To get more information about the selectivity of the lead compound and its mechanism of action, the authors aimed at immobilizing NKI1 derivatives on a SepharoseTM matrix that could be further used in chemical proteomics .
SUMMARY
Nicotinamide adenine dinucleotide (NAD) kinases (NADK) are ubiquitous enzymes, which catalyze the phosphorylation of NAD to nicotinamide_adenine_dinucleotide_phosphate (NADP), which is . . .
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