New insights into car t cell-mediated killing of tumor cells

HIGHLIGHTS

• who: David Espie and Emmanuel Donnadieu from the University of Siena, Italy have published the Article: New insights into CAR T cell-mediated killing of tumor cells, in the Journal: (JOURNAL)
• how: Analyzing malignant B cells from chronic lymphocytic leukemia patients the data indicated that the percentage of activated CD20 CAR T_cells was positively correlated with the amount of ICAM-1 on cancer cells.
• future: Experiments showed that IFNgR signaling on tumor cells was required for sufficient adhesion of CAR T_cells to mediate productive CAR T-cell interaction with tumor cells as well . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.