New insights into conformationally restricted carbonic anhydrase inhibitors

HIGHLIGHTS

  • who: Jacob Combs and collaborators from the Department of Biochemistry and Molecular Biology, College of Medicine, University of Florida, Gainesville, FL, USA have published the research: New Insights into Conformationally Restricted Carbonic Anhydrase Inhibitors, in the Journal: Molecules 2023, 890 of /2023/
  • what: This study examined modes of binding between different compound scaffolds oriented in the active_site of CA isoforms. All compounds reported in this work were investigated for their ability to physiologiAll compounds reported in this work were investigated for their ability to physiologcally icallyinhibit inhibitthe themost mostrelevant relevantCA CAisoforms isoformsI,I,II, II . . .

     

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