New insights into structural disorder in human respiratory syncytial virus phosphoprotein and implications for binding of protein partners*

HIGHLIGHTS

  • who: Nelson Pereira from the (UNIVERSITY) have published the research work: New Insights into Structural Disorder in Human Respiratory Syncytial Virus Phosphoprotein and Implications for Binding of Protein Partners*, in the Journal: (JOURNAL) of February/10,/2017
  • what: The authors show here that two regions identified before as binding regions for Nmono and M2-1 , ␣N1 and ␣N2, respectively, display weak ␣-helical propensity.
  • how: Interactions of hRSV P with Nucleocapsid Analogs-Because transiently structured regions of IDPs are potential molecular recognition elements the authors carried out NMR interaction experiments to investigate the impact . . .

     

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