HIGHLIGHTS
- who: COPYRIGHT et al. from the Fourth Military Medical University, China have published the research work: New insights into the interplay between autophagy and cartilage degeneration in osteoarthritis, in the Journal: (JOURNAL)
- what: The abnormal expression of a set of aggrecanases is the main reason for cartilage degradation (e_g, a disintegrin and metalloproteinase with thrombospondin motifs ADAMTS-4 and -5) and frontiersin.org 10.3389/fcell.2022.1089668 and evaluated therapeutic applications of drugs targeting chondrocyte autophagy in preclinical and clinical research. Meanwhile, the research on drug regulation of OA autophagy focuses on animal research . . .
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