New insights into the regulation of cystathionine beta synthase (cbs), an enzyme involved in intellectual deficiency in down syndrome

HIGHLIGHTS

• who: Pierre Conan from the France France France have published the paper: New insights into the regulation of Cystathionine beta synthase (CBS), an enzyme involved in intellectual deficiency in Down syndrome, in the Journal: (JOURNAL)
• what: The authors show here that, similarly to CYS4-OE, YAK1-OE induced cytosolic acidification and that combined effect of CYS4-OE and YAK1-OE on cytosolic pH was additive . Due to the important role of MCK1/GSK3 in cell signaling, the authors focused the attention on this genetic repressor of CYS4-OE induced phenotypes.
• how: Genetic and . . .
  

   

  

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