New insights of necroptosis and immune infiltration in sepsis-induced myocardial dysfunction from bioinformatics analysis through rna-seq in mice

HIGHLIGHTS

• who: Yan Du et al. from the Shanghai Jiao Tong University, China have published the paper: New insights of necroptosis and immune infiltration in sepsis-induced myocardial dysfunction from bioinformatics analysis through RNA-seq in mice, in the Journal: (JOURNAL)
• what: The authors generated the lipopolysaccharide (LPS)induced myocardial dysfunction model mice through intraperitoneal injections and analyzed the transcriptome changes in the cardiac tissues using bioinformatics analyses. In the present study, GSEA showed that necroptosis was significantly upregulated in SIMD. The study demonstrated significant correlation between necroptosis and immune cell infiltration in SIMD, but further . . .
  

   

  

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