HIGHLIGHTS
SUMMARY
It must be stressed that each one has specific characteristics in terms of its expression of cell surface markers, longterm in_vitro culturing, in_vitro differentiation, potential, immunomodulatory features, and its homing capacity, among others. Specifically, the viability, proliferation, and differentiation through the intracellular activity alkaline phosphatase (ALP) at different culture times have been studied to uncover their potential as new biomaterial and their possible implementation in tissue regeneration engineering for bone regeneration as an initial "in_vitro" test. The MC3T3-E1 cell type is a murine calvaria-derived pre-osteoblastic cell line used as an archetypal . . .
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