New perspectives on the regulation of germinal center reaction via αv&bgr;8- mediated activation of tgf&bgr;

HIGHLIGHTS

  • who: Su00e9bastien This from the University of Massachusetts Medical School, United States have published the research: New perspectives on the regulation of germinal center reaction via u03b1v&bgr;8- mediated activation of TGF&bgr;, in the Journal: (JOURNAL)
  • what: In this review, the authors focus on the role of the Transforming Growth_Factor b (TGFb) in the regulation of humoral immunity in the context of T-dependent response. (D) Despite lack of formal demonstration, the authors propose that, given their molecular arsenal and TGFb-dependent function in the intestinal mucosae, avb8-expressing Foxp3+ T_cells (Treg) could . . .

     

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