New players in neuronal iron homeostasis: insights from crispri studies

HIGHLIGHTS

  • who: Daniel A. Bu00f3rquez and collaborators from the Center for Biomedical Research, Faculty of Medicine, Universidad Diego Portales, Eju00e9rcito Libertador , have published the research: New Players in Neuronal Iron Homeostasis: Insights from CRISPRi Studies, in the Journal: Antioxidants 2022, 11, 1807. of 10/01/2022
  • what: Systematic analysis of huge data obtained from CRISPR-based screenings in a physiologically relevant system (iPSC-derived human glutamatergic neurons) allowed us to hierarchically organize the processes that impact iron accumulation.
  • how: The authors conducted a bioinformatic analysis integrating data obtained from a genome-wide CRISPR interference . . .

     

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