New series of pyrazoles and imidazo-pyrazoles targeting different cancer and inflammation pathways

HIGHLIGHTS

  • who: Maria Grazia Signorello and collaborators from the Lab, Department of Pharmacy, University of Genoa, Viale Benedetto XV , have published the Article: New Series of Pyrazoles and Imidazo-Pyrazoles Targeting Different Cancer and Inflammation Pathways, in the Journal: Molecules 2021, 5735 of /2021/
  • what: All tested compounds showed the ability to interfere with ROS production and p38MAPK phosphorylation with different potency in human platelet, evidencing a potential dual anti-inflammatory and anticancer mechanism of action.
  • future: New investigation will be necessary to investigate the in_vivo anti-angiogenic action of these interesting classes of . . .

     

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