Nexgb: a network embedding framework for anticancer drug combination prediction

HIGHLIGHTS

  • who: Fanjie Meng and collaborators from the School of Computer Science, Qufu Normal University, Rizhao, China have published the paper: NEXGB: A Network Embedding Framework for Anticancer Drug Combination Prediction, in the Journal: (JOURNAL)
  • what: The authors propose network-embeddingbased model which integrates the corresponding protein modules of drug-cancer cell lines with PPI network information. extracts the topological features of each protein node in PPI network by struc2vec. The authors propose a novel framework, extreme gradient boosting for network embedding (NEXGB), that utilizes PPI network information to identify drug combinations with synergistic effects in . . .

     

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