Next-generation heterocyclic electrophiles as small-molecule covalent mura inhibitors

HIGHLIGHTS

• who: Pu00e9ter u00c1bru00e1nyi-Balogh and collaborators from the Faculty of Pharmacy, University of Ljubljana, Askerceva, Ljubljana, Slovenia have published the Article: Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors, in the Journal: Pharmaceuticals 2022, 15,15, x FOR PEER REVIEW Pharmaceuticals 2022, x FOR PEER REVIEW of /2022/
• what: The authors report the second generation of heterocyclic electrophiles: the quaternized analogue of the heterocyclic fragment library with improved reactivity and inhibitory potency. Next, the authors aimed determine theGibbs Gibbsfree freeenergies energiesofof ofactivation activationfor forsome somereprerepreNext, Next, the authors weaimed aimedtoto todetermine determinethe the . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.