Next-generation morphometry for pathomics-data mining in histopathology

HIGHLIGHTS

SUMMARY

    Four cohorts (AC_B, AC_N, HuBMAP, KPMP) covering the whole spectrum of native and transplant pathology were used for development (AC_B and amp; AC_N), testing (AC_B and amp; AC_N) and external validation (KPMP and amp; HuBMAP) of FLASH. The two largest cohorts in this study are AC_B and VALIGA, covering approximately 92% of total cases used. Demographic and clinical characteristics between cohorts were comparable, apart from younger patients and more males in the VALIGA cohort, as well as reduced kidney function assessed by estimated glomerular filtration rate (eGFR), which was more common in the AC_B . . .

     

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