Next-generation sequencing for mrd monitoring in b-lineage malignancies: from bench to bedside

HIGHLIGHTS

  • who: Xinyue Deng from the (UNIVERSITY) have published the paper: Next-generation sequencing for MRD monitoring in B-lineage malignancies: from bench to bedside, in the Journal: (JOURNAL)
  • what: The authors focused on the performance of NGS-based assays compared with conventional approaches and the interpretation of results revealing directions for improvement and prospects in clinical practice.

SUMMARY

    Outcomes in patients with negative MRD at certain time points were observed in multiple studies. MRD negativity is usually defined as less than 1 tumor cell in 100,000 bone marrow (BM) cells . . .

     

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