Nf-κb is a critical mediator of post-mitotic senescence in oligodendrocytes and subsequent white matter loss

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  • who: Judith Stefanie Schlett from the Mice were housed under specific standardized pathogen-free conditions in the animal facility at Ulm UniversityFood and water were provided ad libidum, a, light/12dark cycle was obeyed. IKK2-CAPLP-Cre, was generated by crossing single transgenic Tg(Plp1cre/ERT2) Ueli [82] mice (short PLP-CreERT2) with mice single transgenic for Gt(ROSA) Sortm4(Ikbkb) Rsky [83]. The u00ad RFPPLP-Cre, Cre reporter line was established by crossing single transgenic Tg(Plp1-cre/ ERT2) Ueli [82] mice with mice single transgenic for Gt(ROSA) Sortm Hjf [84]. The R u00adFPPLP-Cre . . .

     

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