HIGHLIGHTS
- who: Alice O&rsquo and collaborators from the Lady Davis Institute (LDI), Canada United Kingdom, Royal Sussex County Hospital, University Hospitals Sussex, Brighton, United Kingdom have published the paper: NF-kB and the CLL microenvironment, in the Journal: (JOURNAL)
- what: The authors explore the components of the microenvironment which activate NF-kB in CLL, identifying potential therapeutic targets for this prevalent and incurable malignancy.
- future: The prevailing direction of crosstalk in non-malignant B cells is non-canonical activity inducing canonical dimers as canonical pathway activity does not induce RelBp52 .
SUMMARY . . .
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