Nfb-mediated mechanisms drive pedf expression and function in pre- and post-menopausal oestrogen levels in breast cancer

HIGHLIGHTS

  • who: Naomi Brook and collaborators from the Curtin Medical School, Curtin University, Bentley, WA, Australia have published the article: NFB-Mediated Mechanisms Drive PEDF Expression and Function in Pre- and Post-Menopausal Oestrogen Levels in Breast Cancer, in the Journal: (JOURNAL)
  • what: The authors propose that status is associated with a PEDF/NFu03baB reciprocal regulatory axis which drives PEDF expression and anti-metastatic function in a subtypespecific manner. The aim of this study was to investigate the potential mechanisms driving differential PEDF expression and function in pre- versus post-menopausal oestrogen conditions in metastatic BC . . .

     

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