Niche deconvolution of the glioblastoma proteome reveals a distinct infiltrative phenotype within the proneural transcriptomic subgroup

HIGHLIGHTS

  • who: K. H. Brian Lam from the (UNIVERSITY) have published the article: Niche deconvolution of the glioblastoma proteome reveals a distinct infiltrative phenotype within the proneural transcriptomic subgroup, in the Journal: (JOURNAL)
  • what: The authors compare the resulting estimates of the relative niche contributions across the distinct transcriptional subtypes to garner potential new biological and clinical insights into this aggressive disease.

SUMMARY

    Glioblastoma is an aggressive form of brain cancer that has seen little change in its clinical outlook in over 50 years1. While historically considered as a single and uniform . . .

     

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