Nicotine-mediated recruitment of gabaergic neurons to a dopaminergic phenotype attenuates motor deficits in an alpha-synuclein parkinson’s model

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• who: Jessica IChi Lai et al. from the Department of Psychiatry, University of California San Diego, La Jolla, CA, USA have published the Article: Nicotine-Mediated Recruitment of GABAergic Neurons to a Dopaminergic Phenotype Attenuates Motor Deficits in an Alpha-Synuclein Parkinsonu2019s Model, in the Journal: (JOURNAL)
• what: The authors investigate the cell-specific mechanism through which chronic nicotine influences the activity-dependent regulation of genes controlling the expression of Nurr1 and the DA-synthesizing enzyme tyrosine hydroxylase (TH) in neurons of the SN, while attenuating some of the PD-associated locomotor deficits. Given that . . .
  

   

  

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