Nilotinib counteracts p-glycoprotein-mediated multidrug resistance and synergizes the antitumoral effect of doxorubicin in soft tissue sarcomas

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• who: Victor Hugo Villar et al. from the Clinical and Translational Research Group, Department of Biology, Institut Universitari d'Investigacions en Ciències la Salut (IUNICS), University of the Balearic Islands, Spain, Department of Oncology University Hospital Son, Spain have published the Article: Nilotinib Counteracts P-Glycoprotein-Mediated Multidrug Resistance and Synergizes the Antitumoral Effect of Doxorubicin in Soft Tissue Sarcomas, in the Journal: (JOURNAL) of May/25,/2012
• what: The study compares the effectiveness and molecular mechanisms involved in the antiproliferative effects of the TK inhibitors, nilotinib and imatinib, as individual therapeutic agents or . . .
  

   

  

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