Nintedanib modulates type iii collagen turnover in viable precision-cut lung slices from bleomycin-treated rats and patients with pulmonary fibrosis

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  • who: Christina Hesse from the (UNIVERSITY) have published the research: Nintedanib modulates type III collagen turnover in viable precision-cut lung slices from bleomycin-treated rats and patients with pulmonary fibrosis, in the Journal: (JOURNAL) of 26/Nov/2021
  • what: This study demonstrated that neoepitope biomarkers of turnover and indicated that C3M is a promising translational neoepitope biomarker of PF in terms of therapy assessment. The inclusion of human PCLS in this study provided the unique opportunity to work directly with parenchymal lung tissues from donors with end-stage IPF and PF, which are otherwise . . .

     

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