Nitazoxanide inhibits acetylated klf5-induced bone metastasis by modulating klf5 function in prostate cancer

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  • who: Qingqing Huang from the Male Balb/c nude mice at, weeks old were purchased from Charles River (Beijing, China)Upon arrival at the Animal Center of the Southern University of Science and Technology (SUSTech), mice were quarantined for one week before use. All mice were maintained and handled following the National Institutes of Health guide for the Care and Use of Laboratory Animals. To measure if NTZ inhibits Ac-KLF5-induced bone metastasis, we used both prevention and therapy modes. For the prevention model, following a recently published method [26], mice were anesthetized, the tail artery . . .

     

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