Nlrp3 inflammasome: the rising star in cardiovascular diseases

HIGHLIGHTS

  • who: Nianguo Dong and Fei Li from the (IRCCS), Italy Konkuk University, South Korea have published the research work: NLRP3 inflammasome: The rising star in cardiovascular diseases, in the Journal: (JOURNAL)
  • what: NLRP3 is a significant PRR in the innate immune system, which can be activated by various PAMPs and DAMPs.
  • how: The results showed that the lesions of mice transplanted with Nlrp3-/- Asc-/- or IL-1u03b1-/-/IL-1u03b2-/- marrow were decreased compared to the wild-type ones. These results indicated that it is not appropriate to simply summarize the role of IL . . .

     

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