Nlrp3 knockout protects against lung injury induced by cerebral ischemia – reperfusion

HIGHLIGHTS

  • who: Cerebral Ischemia-Reperfusion and collaborators from the Central Laboratory, Renmin Hospital of Wuhan University, Wuhan, China have published the article: NLRP3 Knockout Protects against Lung Injury Induced by Cerebral Ischemia - Reperfusion, in the Journal: Oxidative Medicine and Cellular Longevity
  • what: The authors determined the effect of NLRP3 knockout (KO) on ischemic brain and lung injury resulting from stroke by using a middle cerebral artery occlusion (MCAO) focal ischemia mouse model and attempted to further clarify the crosstalk between cerebral ischemia and ALI. The study demonstrated that after NLRP3 KO, NLRP3-related proteins were downregulated . . .

     

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