Nmt1 and nmt2 are lysine myristoyltransferases regulating the arf6 gtpase cycle

HIGHLIGHTS

• who: Tatsiana Kosciuk from the Cornell University have published the research: NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 26/02/2020
• what: While the study provides a mechanism for ARF6 unique plasma 12 membrane targeting, lysine myristoylation may not be its sole driver, since ARF6 K3R did not localize to the Golgi, like other ARFs. For the analysis of the effects of NMT inhibition and NMT2 OE, the same procedure was followed except that NMT2 was cotransfected with WT ARF6 and 2 μM . . .
  

   

  

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