No evidence for selection of hiv-1 with enhanced gag- protease or nef function among breakthrough infections in the caprisa 004 tenofovir microbicide trial

HIGHLIGHTS

  • who: Denis R. Chopera and colleagues from the HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson RMandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa have published the article: No Evidence for Selection of HIV-1 with Enhanced Gag- Protease or Nef Function among Breakthrough Infections in the CAPRISA 004 Tenofovir Microbicide Trial, in the Journal: PLOS ONE | www.plosone.org of August/28,/2013
  • how: The authors conducted a sensitivity analysis on the entire Nef dataset (including the six samples with low expression/ between duplicate measurements (Spearman's r=0.85 . . .

     

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