No-go decay mrna cleavage in the ribosome exit tunnel produces 5⠲-oh ends phosphorylated by trl1

HIGHLIGHTS

• who: Albertas Navickas from the CNRS et Cellulaire des Eucaryotes, Paris, France have published the research work: No-Go Decay mRNA cleavage in the ribosome exit tunnel produces 5⠲-OH ends phosphorylated by Trl1, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors focus on the fate of NGD-cleaved mRNAs, with an initial goal of mapping the sites of mRNA cleavage with accuracy. By analysing these RNAs in detail, the authors show the importance of the 5′-3′ exoribonuclease Xrn1 in the production of 3′-NGD fragments. The authors demonstrate that this 3 . . .
  

   

  

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