No longer married to inflammasome signaling: the diverse interacting pathways leading to pyroptotic cell death

HIGHLIGHTS

  • who: Ashley, Weir and James E., Vince from the The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia have published the Article: No longer married to inflammasome signaling: the diverse interacting pathways leading to pyroptotic cell death, in the Journal: (JOURNAL) of 24/05/2022
  • future: Studies are required to define if IBD and/or arthritis resulting from the loss of other inhibitors of necroptotic cell death specifically RIPK1 and caspase-8 might drive pathological MLKL-mediated NLRP3 inflammasome responses in humans . It will be important that future studies examining the physiological . . .

     

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