Non-canonical autophagy in aging and age-related diseases

HIGHLIGHTS

  • who: LAP (LC and colleagues from the Kunming Institute of Zoology, Chinese Academy of Sciences (CAS), China Sam Houston State University have published the research: Non-canonical autophagy in aging and age-related diseases, in the Journal: (JOURNAL)

SUMMARY

    Post translational modifications such as phosphorylation of LC3B/ATG8 on Thr50 regulates directionality of autophagosome movement toward the cell periphery in mammalian cells and neurons (Nieto-Torres et_al, 2021b) which could potentially influence the fate of autophagosomes. Several recent studies have highlighted these additional roles of ATG8 proteins leading to alternative fates of their . . .

     

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