Non-canonical functions of spliceosome components in cancer progression

HIGHLIGHTS

  • who: Olga M. Ivanova from the (UNIVERSITY) have published the research: Non-canonical functions of spliceosome components in cancer progression, in the Journal: (JOURNAL) of 23/Nov/2022
  • what: In this review, the authors discuss how disturbances in the expression, abundance, and localization of various components of the splicing machinery affect cellular processes (proliferation, cell cycle, cell division, cell death, DNA repair, etc.) important for cancer progression (Fig 1). In this review, the authors focused on functions of spliceosome proteins not associated with alternative splicing of mediator genes . Considering the deep regulatory network of splicing . . .

     

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